LAP2 (TMPO) Rabbit Polyclonal Antibody

CAT#: TA319722

Rabbit Polyclonal Thymopoietin Antibody

Product Images

Western blot analysis of Thymopoietin in HeLa cell lysate with Thymopoietin antibody at 0.25 ug/mLl in (A) the absence and (B) the presence of blocking peptide.

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  Immunofluorescence of Thymopoietin in HeLa cells with Thymopoietin antibody at 5 ug/mL.

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  Immunocytochemistry of Thymopoietin in HeLa cells with Thymopoietin antibody at 2.5 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 0.25 ug/mL, IF: 5 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Thymopoietin antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human Thymopoietin.
• Formulation: Thymopoietin Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Thymopoietin Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: thymopoietin
• Database Link:
  NP_001027454
  Entrez Gene 21917 MouseEntrez Gene 7112 Human
  UniProt ID P42166
• Background: Thymopoietin Antibody: Thymopoietin (TMPO), also known as LAP2, is a widely expressed lem-domain-containing nuclear protein that is thought to play an important role in the regulation of nuclear architecture by binding lamin B1 and chromosomes in a manner regulated by phosphorylation during mitosis. Thymopoietin associates with nucleoplasmic lamins A/C, which are encoded by the dilated cardiomyopathy (DCM) gene LMNA; mutations in Thymopoietin disrupt this binding, suggesting that Thymopoietin may be a candidate disease gene for DCM.
• Synonyms: CMD1T; LAP2; LEMD4; PRO0868; TP

Reference Data

• Protein Families: Stem cell - Pluripotency, Transmembrane