SLC39A6 Rabbit Polyclonal Antibody

CAT#: TA319873

Rabbit Polyclonal ZIP6 Antibody

Product Images

Western blot analysis of ZIP6 in mouse lung tissue lysate with ZIP6 antibody at 1 ug/mL.

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  Immunohistochemistry of ZIP6 in mouse lung tissue with ZIP6 antibody at 5 ug/mL.

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  Immunofluorescence of ZIP6 in mouse lung tissue with ZIP6 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ZIP6 antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP6.
• Formulation: ZIP6 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: ZIP6 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: solute carrier family 39 member 6
• Database Link:
  NP_036451
  Entrez Gene 106957 MouseEntrez Gene 25800 Human
  UniProt ID Q13433
• Background: ZIP6 Antibody: The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.
• Synonyms: LIV-1; ZIP6

Reference Data

• Protein Families: Druggable Genome, Transmembrane