Rabex5 (RABGEF1) Rabbit Polyclonal Antibody

CAT#: TA319896

Rabbit Polyclonal RABEX5 Antibody

Product Images

Western blot analysis of RABEX5 in rat brain tissue lysate with RABEX5 antibody at 1 ug/mL.

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  Immunohistochemistry of RABEX5 in mouse brain tissue with RABEX5 antibody at 5 ug/mL.

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  Immunofluorescence of RABEX5 in mouse brain tissue with RABEX5 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: RABEX5 antibody was raised against a 19 amino acid synthetic peptide near the center terminus of human RABEX5.
• Formulation: RABEX5 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: RABEX5 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: RAB guanine nucleotide exchange factor 1
• Database Link:
  NP_055319
  Entrez Gene 56715 MouseEntrez Gene 360797 RatEntrez Gene 27342 Human
  UniProt ID Q9UJ41
• Background: RABEX5 Antibody: RABEX5 is a guanine nucleotide exchange factor (GEF) that forms a complex with rabaptin-5 and specifically activates Rab5, a small GTPase that plays an essential role in endocytic traffic. RABEX-5 is thought to also interact with another member of the Rab family, Rab22, which targets RABEX5 to early endosomes, allowing it to activate Rab5 and thereby promote Rab5-mediated endosome fusion.
• Synonyms: rabex-5; RABEX5; RAP1