Pokemon (ZBTB7A) Rabbit Polyclonal Antibody

CAT#: TA319921

Rabbit Polyclonal ZBTB7A Antibody

Product Images

Western blot analysis of ZBTB7A in human ovary tissue lysate with ZBTB7A antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of ZBTB7A in human ovary tissue with ZBTB7A antibody at 2.5 ug/mL.

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  Immunofluorescence of ZBTB7A in human ovary tissue with ZBTB7A antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ZBTB7A antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human ZBTB7A.
• Formulation: ZBTB7A Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: ZBTB7A Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: zinc finger and BTB domain containing 7A
• Database Link:
  NP_056982
  Entrez Gene 16969 MouseEntrez Gene 51341 Human
  UniProt ID O95365
• Background: ZBTB7A Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB7A, also known as LRF, was initially identified as a potential target of the LAZ-3/BCL-6 oncogene. Later reports demonstrated that it could bind to the wild-type IST (inducer of short transcripts) elements of HIV-1 long terminal repeats (LTRs) and stimulate Tat activity on the HIV-1 LTR. More recently it ZBTB7A has been recognized as a proto-oncogene whose overexpression contributes to malignancy in breast cancer and functions as a co-repressor of the androgen receptor in prostate cancer cells.
• Synonyms: FBI-1; FBI1; LRF; pokemon; TIP21; ZBTB7; ZNF857A

Reference Data

• Protein Families: Transcription Factors