DDX41 Rabbit Polyclonal Antibody

CAT#: TA319924

Rabbit Polyclonal DDX41 Antibody

Product Images

Western blot analysis of DDX41 in rat brain tissue lysate with DDX41 antibody at 1 ug/mL.

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  Immunohistochemistry of DDX41 in rat brain tissue with DDX41 antibody at 2.5 ug/mL.

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  Immunofluorescence of DDX41 in rat brain tissue with DDX41 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: DDX41 antibody was raised against a 17 amino acid peptide near the amino terminus of human DDX41.
• Formulation: DDX41 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: DDX41 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 68 kDa; Observed: 70 kDa
• Gene Name: DEAD-box helicase 41
• Database Link:
  NP_057306
  Entrez Gene 72935 MouseEntrez Gene 314336 RatEntrez Gene 51428 Human
  UniProt ID Q9UJV9
• Background: DDX41 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. DDX41, also known as Abstrakt, interacts with and regulates the expression of sorting nexin-2 (SNX2), a protein involved in protein sorting in the trans-Golgi network. Recent evidence suggests that DDX41 also plays a role in the innate immune response by sensing intracellular viral DNA, triggering TBK1 and IRF3 activation, leading to a type I interferon immune response.
• Synonyms: ABS

Reference Data

• Protein Families: Druggable Genome