Zinc finger MIZ domain containing protein 1 (ZMIZ1) Rabbit Polyclonal Antibody

CAT#: TA319972

Rabbit Polyclonal ZIMP10 Antibody

Product Images

Western blot analysis of ZIMP10 in K562 cell lysate with ZIMP10 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide

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  Immunofluorescence of ZIMP10 in K562 cells with ZIMP10 antibody at 20 ug/mL.

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  Immunocytochemistry of ZIMP10 in K562 cells with ZIMP10 antibody at 10 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 0.5 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ZIMP10 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ZIMP10.
• Formulation: ZIMP10 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: ZIMP10 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: zinc finger MIZ-type containing 1
• Database Link:
  NP_065071
  Entrez Gene 57178 Human
  UniProt ID Q9ULJ6
• Background: ZIMP10 Antibody: ZIMP10, also known as ZMIZ1, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein initially identified as a transcriptional co-activator of the androgen receptor (AR). ZIMP10 and the related protein ZIMP7 interact with PIAS3 and enhances AR-mediated transcription. Later experiments showed that ZIMP10 is also a co-activator of the p53 tumor suppressor. Mice deficient in ZIMP10 result in embryonic lethality by E10.5; these embryos reveal severe defects in the reorganization of the yolk sac vascular plexus, indicating that ZIMP10 plays an important role in proper vascular development.
• Synonyms: hZIMP10; MIZ; RAI17; TRAFIP10; ZIMP10