Jaml Hamster Monoclonal Antibody [Clone ID: eBio4E10 (4E10)]

CAT#: TA320220

Hamster Anti-Mouse JAML Purified (50 ug)

Product Images

Staining of mouse JAML-transfected CHO cells with 0.5 ug of Armenian Hamster IgG Isotype Control Purified (open histogram) or 0.5 ug of Anti-Mouse JAML Purified (filled histogram) followed by Anti-Armenian Hamster IgG FITC. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: eBio4E10 (4E10)
• Applications: FC
• Recommended Dilution: Flow, IP
• Reactivities: Mouse
• Host: Hamster
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: adhesion molecule, interacts with CXADR antigen 1
• Database Link:
  NP_001005421
  Entrez Gene 270152 Mouse
  UniProt ID Q80UL9
• Background: The eBio4E10 monoclonal antibody reacts with mouse JAML (junctional adhesion molecule-like protein), also known as AMICA. JAML is a glycosylated membrane protein possessing two Ig-like domains in its extracellular domain. JAML is expressed on polymorphonuclear leukocytes (PMN), and is involved in the transmigration of such cells through epithelial tight junctions via interactions between JAML and epithelial coxsackie and adenovirus receptor (CAR). JAML is also expressed on lymphocyte subsets, such as γδ T cell lines, and can provide co-stimulatory signals for cell activation.
• Synonyms: AMICA; CREA7-1; CREA7-4; FLJ37080; Gm638; JAML; MGC118814; MGC118815