Fas Mouse Monoclonal Antibody [Clone ID: 15A7]

CAT#: TA320326

Mouse Anti-Mouse CD95 (APO-1/Fas) Purified (50 ug)

Product Images

Staining of BALB/c thymocytes with 0.5 ug of Mouse IgG1 kappa Isotype Control Purified (open histogram) or 0.5 ug of Anti-Mouse CD95 (APO-1/Fas) Purified (filled histogram) followed by Anti-Mouse IgG FITC. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: 15A7
• Applications: FC
• Recommended Dilution: Flow
• Reactivities: Mouse
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Fas (TNF receptor superfamily member 6)
• Database Link:
  NP_032013
  Entrez Gene 14102 Mouse
  UniProt ID P25446
• Background: The 15A7 monoclonal antibody reacts with mouse CD95 (Fas, Apo-1), a 40-50 kDa member of the TNFR superfamily. CD95 is expressed by a broad range of hematopoietic and non-hematopoietic cells including monocytes, neutrophils, activated lymphocytes and fibroblasts. Interaction of CD95 on mature lymphocytes with its ligand (FasL) induces apoptosis and is thought to be important in peripheral tolerance. 15A7 reacts with mouse CD95 in BALB/c strain and a bit more weakly in C57Bl/6 strain. 15A7 does not induce apoptosis of Fas-expressing cells.
• Synonyms: ALPS1A; APO-1; APT1; CD95; FAIM2; FAS1; FASTM; LFG; NMP35; TNFRSF6