IFNGR2 Mouse Monoclonal Antibody [Clone ID: 4S.B3]
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Specifications
Product Data | |
Clone Name | 4S.B3 |
Recommended Dilution | Flow |
Reactivities | Human |
Host | Mouse |
Clonality | Monoclonal |
Formulation | Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer |
Concentration | lot specific |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | interferon gamma receptor 2 (interferon gamma transducer 1) |
Database Link | |
Background | The 4S.B3 monoclonal antibody reacts with interferon-gamma (IFN gamma). The 4S.B3 antibody is a neutralizing antibody. Human IFN gamma is a 17 kDa factor produced by activated T and NK cells and is an anti-viral and anti-parasitic cytokine. IFN gamma in synergy with other cytokines, such as TNF alpha, inhibits proliferation of normal and transformed cells. Immunomodulatory effects of IFN gamma are exerted on a wide range of cell types expressing the high affinity receptors for IFN gamma. Glycosylation of IFN gamma does not affect its biological activity. |
Synonyms | AF-1; IFGR2; IFNGT1; IMD28 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity |
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in shipping.