ATG4C Goat Polyclonal Antibody

CAT#: TA321018

Goat Polyclonal Anti-ATG4C Antibody

Product Images

ATG4C antibody (2ug/ml) staining of Human Skeletal Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 2-6µg/ml
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: C- terminus of NP_116241.2; NP_835739.1 (EDEKKQLKRFSTEE)
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: autophagy related 4C cysteine peptidase
• Database Link:
  NP_116241
  Entrez Gene 489561 DogEntrez Gene 84938 Human
  UniProt ID Q96DT6
• Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008]
• Synonyms: APG4-C; APG4C; AUTL1; AUTL3
• Note: Reported variants represent identical protein: NP_116241.2, NP_835739.1

Reference Data

• Protein Families: Protease
• Protein Pathways: Regulation of autophagy