Superoxide Dismutase 1 (SOD1) Rabbit Polyclonal Antibody

CAT#: TA321133

Anti-SOD1 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 16 kDa. Positive control: Mouse liver tissue lysate. Recommended dilution: 1/1000-5000. (Gel: 12%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/1160 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 45 seconds)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:2000-10000, WB: 1:1000-5000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 2-159 amino acids of human superoxide dismutase 1, soluble
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 16 kDa
• Gene Name: superoxide dismutase 1, soluble
• Database Link:
  NP_000445
  Entrez Gene 20655 MouseEntrez Gene 24786 RatEntrez Gene 6647 Human
  UniProt ID P00441
• Background: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein; acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.?
• Synonyms: ALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Amyotrophic lateral sclerosis (ALS), Huntington's disease, Prion diseases