Neuropeptide Y (NPY) Rabbit Polyclonal Antibody

CAT#: TA321231

Anti-NPY Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

Product Images

Specifications

Product Data
Applications WB
Recommended Dilution WB: 1000-5000
WB positive control: Mouse adrenal gland tissue lysate
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Full length fusion protein
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 11 kDa
Gene Name neuropeptide Y
Background This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes; including cortical excitability; stress response; food intake; circadian rhythms; and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase; activate mitogen-activated protein kinase (MAPK); regulate intracellular calcium levels; and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels; higher alcohol consumption; and may be a risk factor for various metabolic and cardiovascular diseases.
Synonyms PYY4
Reference Data
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Adipocytokine signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.