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ARF6 Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommended Dilution | WB: 500-2000 WB positive control: HepG2 and 231 cells IHC: 10-50 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 162-175 amino acids of Human ADP-ribosylation factor 6 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 20 kDa |
| Gene Name | ADP ribosylation factor 6 |
| Database Link | |
| Background | This gene encodes a member of the human ARF gene family; which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane; and regulates vesicular trafficking; remodelling of membrane lipids; and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. |
| Synonyms | DKFZp564M0264 |
| Reference Data | |
| Protein Pathways | Endocytosis, Fc gamma R-mediated phagocytosis |
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