Hsp105 (HSPH1) Rabbit Polyclonal Antibody

CAT#: TA321775

Anti-HSPH1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: PC3 cells, human colon cancer and liver cancer tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 300 amino acids of human heat shock 105kDa/110kDa protein 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 97 kDa
• Gene Name: heat shock protein family H (Hsp110) member 1
• Database Link:
  NP_006635
  Entrez Gene 15505 MouseEntrez Gene 288444 RatEntrez Gene 10808 Human
  UniProt ID Q92598
• Background: Heat shock protein 105 kDa?is a?protein?that in humans is encoded by the?HSPH1?gene. Prevents the aggregation of denatured proteins in cells under severe stress; on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. Highly expressed in testis. Present at lower levels in most brain regions; except cerebellum. Overexpressed in cancer cells. Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.
• Synonyms: HSP105; HSP105A; HSP105B; NY-CO-25

Reference Data

• Protein Families: Stem cell - Pluripotency