MURF1 (TRIM63) Rabbit Polyclonal Antibody

CAT#: TA322135

Anti-TRIM63 Rabbit Polyclonal Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane: Rat skeletal muscle tissue lysate Primary antibody: TA322135 (TRIM63 Antibody) at dilution 1/800 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA322135 (TRIM63 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA322135 (TRIM63 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Rat skeletal muscle tissue lysate
  IHC: 50-200
  Positive control: Human colorectal cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide peptide corresponding to a region derived from 2-14 amino acids of human tripartite motif containing 63, E3 ubiquitin protein ligase
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 40 kDa
• Gene Name: tripartite motif containing 63
• Database Link:
  NP_115977
  Entrez Gene 140939 RatEntrez Gene 433766 MouseEntrez Gene 84676 Human
  UniProt ID Q969Q1
• Background: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins; myosin light chain; myosin binding protein; and for muscle-type creatine kinase.
• Synonyms: IRF; MURF1; MURF2; RNF28; SMRZ