RHEB Rabbit Polyclonal Antibody

CAT#: TA322575

Anti-RHEB Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 150-162 amino acids of Human Ras homolog enriched in brain
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Ras homolog enriched in brain
• Database Link:
  NP_005605
  Entrez Gene 19744 MouseEntrez Gene 26954 RatEntrez Gene 6009 Human
  UniProt ID Q15382
• Background: This gene is a member of the small GTPase superfamily and encodes a lipid-anchored; cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form; and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped; two on chromosome 10 and one on chromosome 22.
• Synonyms: RHEB2

Reference Data

• Protein Pathways: Insulin signaling pathway, mTOR signaling pathway