CST8 Rabbit Polyclonal Antibody

CAT#: TA322601

Anti-CST8 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 16 kDa. Positive control: Testis tissue, HEK-293 and DU145 cell lysate. Recommended dilution: 1/500-2000. (Gel: 12%SDS-PAGE Lane 1: Testis tissue lysate Lane 2: HEK-293 cell lysate Lane 3: DU145 cell lysate Lysates: 40 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 90 amino acids of human cystatin 8 (cystatin-related epididymal specific)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 16 kDa
• Gene Name: cystatin 8
• Database Link:
  NP_005483
  Entrez Gene 13012 MouseEntrez Gene 29679 RatEntrez Gene 10047 Human
  UniProt ID O60676
• Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar to type 2 cystatins. The protein exhibits highly tissue-specific expression in the reproductive tract, suggesting implicit roles in reproduction. Alternative splicing identified in mouse is suggested in human based on EST evidence but the full-length nature of putative variants has not been determined.
• Synonyms: CRES; CTES5

Reference Data

• Protein Families: Secreted Protein