ABCD4 Rabbit Polyclonal Antibody

CAT#: TA322672

Anti-ABCD4 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications WB
Recommended Dilution WB: 500-2000
WB positive control: Jurkat cells
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 137-149 amino acids of human ATP-binding cassette, sub-family D (ALD), member 4
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 69 kDa
Gene Name ATP binding cassette subfamily D member 4
Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1; MDR/TAP; MRP; ALD; OABP; GCN20; White). This protein is a member of the ALD subfamily; which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However; it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and; therefore; may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis.
Synonyms ABC41; EST352188; MAHCJ; P70R; P79R; PMP69; PXMP1L
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways ABC transporters

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