Profilin 1 (PFN1) Rabbit Polyclonal Antibody

CAT#: TA322681

Anti-PFN1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Jurkat and 231 cells
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 2-140 amino acids of human profilin 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 15 kDa
• Gene Name: profilin 1
• Database Link:
  NP_005013
  Entrez Gene 18643 MouseEntrez Gene 64303 RatEntrez Gene 5216 Human
  UniProt ID P07737
• Background: This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome; and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.?
• Synonyms: ALS18

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Regulation of actin cytoskeleton