FOXN1 Rabbit Polyclonal Antibody

CAT#: TA322840

Anti-FOXN1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm, Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 586-600 amino acids of Human forkhead box N1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: forkhead box N1
• Database Link:
  NP_003584
  Entrez Gene 15218 MouseEntrez Gene 287469 RatEntrez Gene 8456 Human
  UniProt ID O15353
• Background: Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia; resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency; the skin disorder congenital alopecia; and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed.
• Synonyms: FKHL20; RONU; WHN

Reference Data

• Protein Families: Druggable Genome, Transcription Factors