TXN Rabbit Polyclonal Antibody

CAT#: TA322867

Anti-TXN Rabbit Polyclonal Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane 1-2: A172 cells hela cells Primary antibody: TA322867 (TXN Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA322867 (TXN Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA322867 (TXN Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA322867 (TXN Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA322867 (TXN Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: A172 and hela cells
  IHC: 25-100
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm, Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 91-105 amino acids of human thioredoxin
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 12 kDa
• Gene Name: thioredoxin
• Database Link:
  NP_003320
  Entrez Gene 7295 Human
  UniProt ID P10599
• Background: The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins; which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
• Synonyms: TRDX; TRX; TRX1

Reference Data

• Protein Families: Druggable Genome