ID4 Rabbit Polyclonal Antibody

CAT#: TA323154

Anti-ID4 Rabbit Polyclonal Antibody


USD 345.00

4 Weeks*

Size
    • 100 ul

Product Images

Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 20-100
Positive control: Human esophagus cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 19-38 amino acids of Human inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name inhibitor of DNA binding 4, HLH protein
Background DNA-binding protein inhibitor ID-4?is a?protein?that in humans is encoded by the?ID4?gene. Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative (antimorph) HLH proteins encoded by Id-related genes; such as ID4; also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently; Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins .
Synonyms bHLHb27; IDB4
Reference Data
Protein Families ES Cell Differentiation/IPS, Transcription Factors
Protein Pathways TGF-beta signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.