PEG10 Rabbit Polyclonal Antibody

CAT#: TA323342

Anti-PEG10 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: 231 and A549 cells
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 250 amino acids of human paternally expressed 10
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 80 kDa
• Gene Name: paternally expressed 10
• Database Link:
  NP_001035242
  Entrez Gene 170676 MouseEntrez Gene 102553587 RatEntrez Gene 23089 Human
  UniProt ID Q86TG7
• Background: This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs); RF1 and RF1/RF2; as well as retroviral-like slippage and pseudoknot elements; which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants; as well as from use of upstream non-AUG (CUG) start codon; have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.
• Synonyms: EDR; HB-1; Mar2; Mart2; MEF3L; RGAG3