VMA21 Rabbit Polyclonal Antibody

CAT#: TA323385

Anti-VMA21 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IF, IHC
• Recommended Dilution: IHC: 150-500
  Positive control: Human esophagus cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 3-16 amino acids of human VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
• Database Link:
  NP_001017980
  Entrez Gene 67048 MouseEntrez Gene 501658 RatEntrez Gene 203547 Human
  UniProt ID Q3ZAQ7
• Background: This gene encodes a chaperone for assembly of lysosomal vacuolar ATPase. Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. Associates with the V0 complex of the vacuolar ATPase (V-ATPase). MEAX is a childhood-onset disease characterized by progressive vacuolation and atrophy of skeletal muscle. It is inherited in recessive fashion; affecting boys and sparing carrier females. Onset is in childhood; and patients exhibit weakness of the proximal muscles of the lower extremities; progressing slowly to involve other skeletal muscle groups over time.
• Synonyms: MEAX; XMEA

Reference Data

• Protein Families: Transmembrane