NQO1 Rabbit Polyclonal Antibody

CAT#: TA323406

Anti-NQO1 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

Other products for "NQO1"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: Hela cells
IHC: 25-100
Positive control: Human liver cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 260-274 amino acids of Human NAD(P)H dehydrogenase, quinone 1
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 27 kDa
Gene Name NAD(P)H quinone dehydrogenase 1
Background This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD); an increased risk of hematotoxicity after exposure to benzene; and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants; encoding different isoforms; have been characterized.
Synonyms DHQU; DIA4; DTD; NMOR1; NMORI; QR1
Reference Data
Protein Families Druggable Genome

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