Doublecortin (DCX) Rabbit Polyclonal Antibody

CAT#: TA323627

Anti-DCX Rabbit Polyclonal Antibody

Product Images

Predicted band size: 45 kDa. Positive control: Molt-4 and Hela cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lane 1, 2: Molt-4 and Hela cells lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide sequence around aa.413~417( P-T-S-P-G) derived from Human Doublecortin.
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45 kDa
• Gene Name: doublecortin
• Database Link:
  NP_000546
  Entrez Gene 13193 MouseEntrez Gene 84394 RatEntrez Gene 1641 Human
  UniProt ID O43602
• Background: Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of an overlapping, but distinct, signaling pathways that promote neuronal migration.
• Synonyms: DBCN; DC; LISX; SCLH; XLIS

Reference Data

• Protein Families: Druggable Genome