Calpain 1 (CAPN1) Rabbit Polyclonal Antibody

CAT#: TA324116

Anti-CAPN1 Rabbit Polyclonal Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-3: K562 Jurkat and Hela cell lysates Primary antibody: TA324116 (CAPN1 Antibody) at dilution 1/1000 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 30 seconds

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA324116 (CAPN1 Antibody) at dilution 1/75 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA324116 (CAPN1 Antibody) at dilution 1/75, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA324116 (CAPN1 Antibody) at dilution 1/75 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA324116 (CAPN1 Antibody) at dilution 1/75, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: K562, Jurkat and Hela cell lysates
  IHC: 50-200
  Positive control: Human tonsil
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 543-713 amino acids of Human Calpain-1 catalytic subunit
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 82 kDa
• Gene Name: calpain 1
• Database Link:
  NP_001185797
  Entrez Gene 12333 MouseEntrez Gene 29153 RatEntrez Gene 823 Human
  UniProt ID P07384
• Background: The calpains; calcium-activated neutral proteases; are nonlysosomal; intracellular cysteine proteases. The mammalian calpains include ubiquitous; stomach-specific; and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large; catalytic subunits associated with a common small; regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme; calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
• Synonyms: CANP; CANP1; CANPL1; muCANP; muCL; SPG76

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Alzheimer's disease, Apoptosis