SREBP1 (SREBF1) Rabbit Polyclonal Antibody

CAT#: TA325882

Rabbit Polyclonal SREBP-1 (Ser439) Antibody (Phospho-specific)

Product Images

Western blot analysis of SREBP-1 phosphorylation expression in TNF treated Jurkat whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
• Reactivities: Human, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human SREBP-1 around the phosphorylation site of Serine 439
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 122 kDa
• Gene Name: sterol regulatory element binding transcription factor 1
• Database Link:
  NP_001005291
  Entrez Gene 78968 RatEntrez Gene 6720 Human
  UniProt ID P36956
• Background: This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum.
• Synonyms: bHLHd1; SREBP-1c; SREBP1; SREBP1a

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Insulin signaling pathway