CENPA Mouse Monoclonal Antibody [Clone ID: 5A7-2E11]

CAT#: TA326348

Mouse monoclonal CENP-A Antibody


USD 385.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Clone Name 5A7-2E11
Applications WB
Recommended Dilution WB: 1:1000
Reactivities Human. Other species not yet tested
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Synthetic peptide corresponding to a portion of human CENP-A.
Formulation PBS, 50% glycerol
Concentration lot specific
Purification Protein G Purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name centromere protein A
Background A replicated chromosome includes two kinetochores that control chromosome segregation during mitosis. The Centromere Protein-A, CENP-A, is a Histone H3-like protein that contains a C-terminal H3-like domain, which is required for centromere localization of CENP-A, and an antigenic N-terminal domain.CENP-A, originally isolated from HeLa cells, is essential for kinetochore targeting of CENP-C. In the presence of DNA CENP-A forms an octa-meric complex with histones H4, H2A, H2B. CENP-A specifically localizes to active centromeres and is a component of specializedcentromeric nucleosomes, on which kinetochores are assembled. CENP-A is essential for nucleosomal packaging of centromeric DNA at interphase and functions as a centromere formation marker on the chromosome.
Synonyms CenH3; CENP-A
Note Detects ~18kDa. Recognizes Human CENP-A
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.