Hsp105 (HSPH1) Rabbit Polyclonal Antibody [Clone ID: N/A]

CAT#: TA326392

Rabbit polyclonal Hsp110 Antibody

Product Images

Western blot analysis of Hsp110 in a human cell mix using a 1:1000 dilution of the antibody

Specifications

Product Data

• Clone Name: N/A
• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Hamster, Human, Monkey, Mouse, Rat, Sheep, Yeast, Cow
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide derived from the sequence of hamster Hsp110; sequence identical to human and mouse
• Formulation: PBS pH7.2, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: heat shock protein family H (Hsp110) member 1
• Database Link:
  NP_006635
  Entrez Gene 15505 MouseEntrez Gene 288444 RatEntrez Gene 721956 MonkeyEntrez Gene 10808 Human
  UniProt ID Q92598
• Background: Hsp110 belongs to a family of large stress proteins known as the Hsp110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied Hsp70 family. They share 30-33% amino acid identity, mostly in the conserved ATP-binding domain . Hsp110 cooperates with Hsp70 in protein folding in the eukaryotic cytosol . In mammals, Hsp110 is constitutively expressed, but exhibits particularly high levels in the brain. Both Hsp70 and Hsp110 are elevated after cerebral ischemia. Recent studies demonstrate that the protective effects of Hsp110 deficiency in cerebral ischemia may partly be mediated by an increase in the chaperone activity of Hsp70 . Studies also suggest that Hsp110 can be used in heat shock protein-based cancer immunotherapy .
• Synonyms: HSP105; HSP105A; HSP105B; NY-CO-25
• Note: Detects ~110kDa

Reference Data

• Protein Families: Stem cell - Pluripotency