TBX21 Rabbit Polyclonal Antibody

CAT#: TA326655

Rabbit Polyclonal TBX21 Antibody

Product Images

Western blot analysis of TBX21 in 293 cell lysate with TBX21 antibody at 1 ug/ml.

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  Immunofluorescence of TBX21 in 293 cells with TBX21 antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: TBX21 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human TBX2.
• Formulation: TBX21 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: TBX21 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 59 kDa; Observed: 55 kDa
• Gene Name: T-box 21
• Database Link:
  NP_037483
  Entrez Gene 57765 MouseEntrez Gene 30009 Human
  UniProt ID Q9UL17
• Background: TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box (1,2). Members of this family include transcription factors involved in the regulation of developmental processes (2). Studies in mouse and humans show that TBX21 is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (1,3). Expression of the human ortholog also correlates with interferon-gamma expression in Th1 and natural killer cells, suggesting a TBX21 may play a role in initiating Th1 lineage development from naive Th precursor cells. (3).
• Synonyms: T-bet; T-PET; TBET; TBLYM

Reference Data

• Protein Families: Druggable Genome, Transcription Factors