ARF6 Rabbit Polyclonal Antibody

CAT#: TA326709

Rabbit Polyclonal ARF6 Antibody

Product Images

Western blot analysis of ARF6 in rat liver tissue lysate with ARF6 antibody at 1 ug/ml.

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  Immunohistochemistry of ARF6 in human kidney tissue with ARF6 antibody at 5 ug/mL.

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  Immunofluorescence of ARF6 in human kidney tissue with ARF6 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ARF6 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ARF6.
• Formulation: ARF6 antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: ARF6 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 19 kDa; Observed: 18 kDa
• Gene Name: ADP ribosylation factor 6
• Database Link:
  NP_001654
  Entrez Gene 11845 MouseEntrez Gene 79121 RatEntrez Gene 382 Human
  UniProt ID P62330
• Background: The ADP-ribosylation factor 6 (ARF6) is a member of the ARF family, which is part of the RAS superfamily (1). The ARF proteins are small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D (2). The product of this gene is localized to the plasma membrane (3), and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling (4).
• Synonyms: DKFZp564M0264

Reference Data

• Protein Pathways: Endocytosis, Fc gamma R-mediated phagocytosis