TDP43 (TARDBP) Rabbit Polyclonal Antibody

CAT#: TA326978

Rabbit anti-TARDBP Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using TARDBP antibody.

Specifications

Product Data

• Applications: ELISA, IHC, IP, RIP, WB
• Recommended Dilution: WB,1:500 - 1:2000
  IHC-P,1:50 - 1:200
  IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
  ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
  RIP,1:20 - 1:50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45kDa
• Gene Name: TAR DNA binding protein
• Database Link:
  NP_031401
  Entrez Gene 230908 MouseEntrez Gene 298648 RatEntrez Gene 23435 Human
  UniProt ID Q13148
• Background: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
• Synonyms: ALS10; TDP-43

Reference Data

• Protein Families: Transcription Factors