RhoGDI (ARHGDIA) Rabbit Polyclonal Antibody

CAT#: TA327001

Rabbit anti-ARHGDIA Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using ARHGDIA antibody.

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  Immunofluorescence analysis of HeLa cell using ARHGDIA antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ELISA, ICC/IF, WB
• Recommended Dilution: WB,1:500 - 1:1000
  IF/ICC,1:50 - 1:200
  ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 23kDa
• Gene Name: Rho GDP dissociation inhibitor alpha
• Database Link:
  NP_004300
  Entrez Gene 192662 MouseEntrez Gene 360678 RatEntrez Gene 396 Human
  UniProt ID P52565
• Background: This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.
• Synonyms: GDIA1; HEL-S-47e; NPHS8; RHOGDI; RHOGDI-1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Neurotrophin signaling pathway