CBS Rabbit Polyclonal Antibody

CAT#: TA327044

Rabbit anti-CBS Polyclonal Antibody

Product Images

Western blot analysis of extracts of mouse kidney tissue, using CBS antibody.

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  Immunofluorescence analysis of U2OS cell using CBS antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, WB
• Recommended Dilution: WB 1:500 - 1:2000;IF 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CBS
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cystathionine-beta-synthase
• Database Link:
  NP_000062
  Entrez Gene 12411 MouseEntrez Gene 24250 RatEntrez Gene 875 Human
  UniProt ID P35520
• Background: The CBS gene encodes cystathionine beta-synthase, which catalyzes the first irreversible step of transsulfuration. The CBS enzyme is a homotetramer of 63-kD subunits and requires pyridoxal phosphate and heme for activity(PMID:11230183). CBS protein is localized in most areas of the brain, but predominantly in the cell bodies and neuronal processes of Purkinje cells and Ammons horn neurons(PMID:12588964). This antibody is specific to CBS.
• Synonyms: HIP4

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cysteine and methionine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Selenoamino acid metabolism