ARSA Rabbit Polyclonal Antibody

CAT#: TA327157

ARSA Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using ARSA antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human ARSA
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: arylsulfatase A
• Database Link:
  NP_000478
  Entrez Gene 11883 MouseEntrez Gene 410 Human
  UniProt ID P15289
• Background: The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2010]
• Synonyms: MLD

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Lysosome, Sphingolipid metabolism