SRP1 (KPNA1) Rabbit Polyclonal Antibody

CAT#: TA327159

Rabbit anti-KPNA1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using KPNA1 antibody.

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  Immunohistochemistry of paraffin-embedded human lung cancer using KPNA1 antibody at dilution of 1:200 (400x lens).

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  Immunohistochemistry of paraffin-embedded rat lung using KPNA1 antibody at dilution of 1:200 (400x lens).

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human KPNA1
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: karyopherin subunit alpha 1
• Database Link:
  NP_002255
  Entrez Gene 16646 MouseEntrez Gene 288064 RatEntrez Gene 3836 Human
  UniProt ID P52294
• Background: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.
• Synonyms: IPOA5; NPI-1; RCH2; SRP1