Clcn5 Rabbit Polyclonal Antibody

CAT#: TA328780

Rabbit Polyclonal Anti-CLC-5


USD 585.00

3 Weeks*

Size
    • 200 ul

Product Images

Other products for "Clcn5"

Specifications

Product Data
Applications WB
Recommended Dilution WB: 1:200-1:2000; IHC: 1:100-1:3000
Reactivities Rat
Host Rabbit
Clonality Polyclonal
Immunogen Peptide CDYENHFNTSKGGEL, corresponding to amino acid residues 401-415 of rat CLC5. Extracellular.
Formulation Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.025% NaN3.
Purification Affinity purified on immobilized antigen.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name chloride voltage-gated channel 5
Background CLC5 is a member of the voltage-dependent Cl channel family that includes nine known members. Based on sequence similarity, CLC5 is closely linked to the CLC3 and CLC4 subunits. Mutations in the CLC5 gene cause Dent's disease a X-linked renal disorder. CLC-5 is mainly found in intracellular vesicles, particularly in early endosomes vesicles, where it is believed to contribute to their acidification. The channel is mainly expressed in the kidney, although it has been found also in small intestine, brain and liver.
Synonyms ClC-5; CLC5; CLCK2; DENTS; hCIC-K2; hClC-K2; NPHL1; NPHL2; OTTHUMP00000023279; OTTHUMP00000023281; XLRH; XRN
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.