Kcnj12 Rabbit Polyclonal Antibody

CAT#: TA328946

Rabbit polyclonal Anti-Kir2.2

Product Images

Western blot analysis of rat kidney (1, 3) and brain (2, 4) membranes: 1, 2. Anti-Kir2.2 antibody, (1:200). 3, 4. Anti-Kir2.2 antibody, preincubated with the control peptide antigen.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:200-1:2000; FC: 1:50-1:600
• Reactivities: Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide (C)EVATDRDGRSPQPEHDFDRÂ corresponding to amino acid residues 391-409 of rat Kir2.2 . Intracellular, C-terminal part.
• Formulation: Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: Phosphate buffered saline (PBS) pH 7.4, 1% BSA, 0.025% NaN3.
• Purification: Affinity purified on immobilized antigen.
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: potassium voltage-gated channel subfamily J member 12
• Database Link:
  NP_446433
  Entrez Gene 117052 Rat
• Background: Kir2.2 is a member of the inward rectifying K+ channel family. The Kir2 subfamily comprises 4 known members: Kir2.1, Kir2.2, Kir2.3 and Kir2.4. The Kir2 subfamily members are strong inward rectifiers and are believed to be involved in maintaining the resting membrane potential and buffering of extracellular K+. The Kir2.2 subunit is expressed in the CNS, kidney and heart where it was found to form heteromeric channels with Kir2.1.
• Synonyms: FLJ14167; hIRK; hIRK1; hkir2.2x; IRK2; kcnj12x; KCNJN1; Kir2.2; Kir2.2v