Neurofilament (NEFM) Rabbit Polyclonal Antibody

CAT#: TA331275

Rabbit Polyclonal Anti-NEFM Antibody

Product Images

WB Suggested Anti-NEFM Antibody; Titration: 1.0 ug/ml; Positive Control: ACHN Whole Cell

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for Anti-NEFM antibody is: synthetic peptide directed towards the C-terminal region of Human NEFM. Synthetic peptide located within the following region: EVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVV
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 59 kDa
• Gene Name: neurofilament, medium polypeptide
• Database Link:
  NP_001099011
  Entrez Gene 4741 Human
  UniProt ID P07197
• Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
• Synonyms: NEF3; NF-M; NFM
• Note: Human: 100%; Sheep: 93%; Bovine: 93%; Rabbit: 93%; Dog: 86%; Rat: 86%; Horse: 86%

Reference Data

• Protein Pathways: Amyotrophic lateral sclerosis (ALS)