LOX 1 (OLR1) Rabbit Polyclonal Antibody

CAT#: TA332415

Rabbit anti-OLR1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using OLR1 antibody.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB,1:100 - 1:500
  ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Formulation: Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 31kDa
• Gene Name: oxidized low density lipoprotein receptor 1
• Database Link:
  NP_002534
  Entrez Gene 108078 MouseEntrez Gene 4973 Human
  UniProt ID P78380
• Background: This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
• Synonyms: CLEC8A; LOX1; LOXIN; SCARE1; SLOX1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: PPAR signaling pathway