Oct-1 (POU2F1) Rabbit Polyclonal Antibody

CAT#: TA332419

Rabbit anti-POU2F1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using POU2F1 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human POU2F1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: POU class 2 homeobox 1
• Database Link:
  NP_002688
  Entrez Gene 18986 MouseEntrez Gene 171068 Rat
  UniProt ID P14859
• Background: Oct-1 (POU2F1) is a ubiquitously expressed, octamer-binding transcription factor containing a POU domain with a homeobox subdomain (1). Oct-1 has been shown to interact with several transcription factors in mediating specific gene expression, including SNAPc (2), OBF-1 (a B-cell transcriptional coactivator protein) (3), TFIIB (4), and TBP (TATA-box-binding protein) (5). Its POU DNA-binding domain allows Oct-1 the flexibility to facilitate the binding and recruitment of several tissue-specific cofactors to either positively or negatively regulate a variety of genes, exerting an important role in development (6).
• Synonyms: oct-1B; OCT1; OTF1

Reference Data

• Protein Families: Druggable Genome, Transcription Factors