EIF5A Rabbit Polyclonal Antibody

CAT#: TA332499

Rabbit anti-EIF5A Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using EIF5A antibody.

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  Immunohistochemistry of paraffin-embedded human kidney using EIF5A antibody at dilution of 1:200 (200x lens).

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  Immunohistochemistry of paraffin-embedded human kidney cancer using EIF5A antibody at dilution of 1:200 (200x lens).

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  Immunohistochemistry of paraffin-embedded human liver using EIF5A antibody at dilution of 1:200 (200x lens).

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  Immunofluorescence analysis of U2OS cell using EIF5A antibody. Blue: DAPI for nuclear staining.

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Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50 - 1:200;IF 1:50 - 1:200
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human EIF5A
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 154
• Gene Name: eukaryotic translation initiation factor 5A
• Database Link:
  NP_001961
  Entrez Gene 276770 MouseEntrez Gene 1984 Human
  UniProt ID P63241
• Background: mRNA-binding protein involved in translation elongation. Has an important function at the level of Mrna turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
• Synonyms: EIF-5A; EIF5A1; eIF5AI