Hsp47 (SERPINH1) Rabbit Polyclonal Antibody

CAT#: TA332536

Rabbit anti-SERPINH1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using SERPINH1 antibody.

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  Immunohistochemical of paraffin-embedded human endometrial cancer using SERPINH1 antibody at dilution of 1:100 (400x lens).

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  Immunohistochemical of paraffin-embedded human breast cancer using SERPINH1 antibody at dilution of 1:100 (200x lens).

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  Immunohistochemical of paraffin-embedded rat kidney using SERPINH1 antibody at dilution of 1:100 (200x lens).

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  Immunofluorescence analysis of HeLa cell using SERPINH1 antibody. Blue: DAPI for nuclear staining.

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Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200;IF 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human SERPINH1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 418
• Gene Name: serpin family H member 1
• Database Link:
  NP_001226
  Entrez Gene 12406 MouseEntrez Gene 29345 RatEntrez Gene 871 Human
  UniProt ID P50454
• Background: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
• Synonyms: AsTP3; CBP1; CBP2; gp46; HSP47; OI10; PIG14; PPROM; RA-A47; SERPINH2

Reference Data

• Protein Families: Druggable Genome