RACGAP1 Rabbit Polyclonal Antibody

CAT#: TA332591

Rabbit anti-RACGAP1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using RACGAP1 antibody.

• 

  Immunohistochemistry of paraffin-embedded human kidney cancer using RACGAP1 antibody at dilution of 1:200 (x400 lens)

• 

  Immunohistochemistry of paraffin-embedded human stomach using RACGAP1 antibody at dilution of 1:200 (x400 lens)

• 

  Immunofluorescence analysis of U20S cell using RACGAP1 antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50 - 1:200;IF 1:50 - 1:200
• Reactivities: Mouse, Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human RACGAP1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 71 kDa
• Gene Name: Rac GTPase activating protein 1
• Database Link:
  NP_037409
  Entrez Gene 26934 MouseEntrez Gene 315298 RatEntrez Gene 29127 Human
  UniProt ID Q9H0H5
• Background: The protein encoded by this gene belongs to the GTPase-activating protein (GAP) family. GAPs bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, GAPs negatively regulate Rho-mediated signals. This protein plays a regulatory role in initiation of cytokinesis, controlling cell growth and differentiation of hematopoietic cells, regulating spermatogenesis, and in neuronal proliferation. Alternatively spliced transcript variants have been found for this gene.
• Synonyms: CYK4; HsCYK-4; ID-GAP; MgcRacGAP

Reference Data

• Protein Families: Druggable Genome