Calcipressin 1 (RCAN1) Rabbit Polyclonal Antibody

CAT#: TA332613

Rabbit anti-RCAN1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using RCAN1 antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human RCAN1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 252
• Gene Name: regulator of calcineurin 1
• Database Link:
  NP_981963
  Entrez Gene 54720 MouseEntrez Gene 266766 RatEntrez Gene 1827 Human
  UniProt ID P53805
• Background: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.
• Synonyms: ADAPT78; CSP1; DSC1; DSCR1; MCIP1; RCN1

Reference Data

• Protein Families: Transcription Factors