Properdin (CFP) Rabbit Polyclonal Antibody

CAT#: TA332666

Rabbit anti-CFP Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using CFP antibody.

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  Immunofluorescence analysis of U20S cell using CFP antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200;IF 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CFP
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 469
• Gene Name: complement factor properdin
• Database Link:
  NP_002612
  Entrez Gene 18636 MouseEntrez Gene 299314 RatEntrez Gene 5199 Human
  UniProt ID P27918
• Background: This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Synonyms: BFD; PFC; PFD; PROPERDIN

Reference Data

• Protein Families: Secreted Protein