Proteasome subunit beta type 2 (PSMB2) Rabbit Polyclonal Antibody

CAT#: TA332716

Rabbit anti-PSMB2 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using PSMB2 antibody.

• 

  Immunohistochemistry of paraffin-embedded human thyroid cancer using PSMB2 antibody at dilution of 1:200 (400x lens).

Specifications

Product Data

• Applications: IHC, IP, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human PSMB2
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 201
• Gene Name: proteasome subunit beta 2
• Database Link:
  NP_002785
  Entrez Gene 26445 MouseEntrez Gene 29675 RatEntrez Gene 5690 Human
  UniProt ID P49721
• Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Synonyms: HC7-I

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Proteasome