RBPJK (RBPJ) Rabbit Polyclonal Antibody

CAT#: TA332834

Rabbit anti-RBPJ Polyclonal Antibody

Product Images

Western blot analysis of extracts of mouse lung, using RBPJ antibody.

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  Immunohistochemistry of paraffin-embedded Human gastric using RBPJ antibody at dilution of 1:100 (x40 lens).

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  Immunohistochemistry of paraffin-embedded Human gastric cancer using RBPJ antibody at dilution of 1:100 (x40 lens).

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50 - 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human RBPJ
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 55 kDa
• Gene Name: recombination signal binding protein for immunoglobulin kappa J region
• Database Link:
  NP_005340
  Entrez Gene 19664 MouseEntrez Gene 679028 RatEntrez Gene 3516 Human
  UniProt ID Q06330
• Background: The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.
• Synonyms: AOS3; CBF1; csl; IGKJRB; IGKJRB1; KBF2; RBP-J; RBPJK; RBPSUH; SUH

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: Notch signaling pathway