Mannan Binding Lectin (MBL2) Rabbit Polyclonal Antibody

CAT#: TA332941

Rabbit anti-MBL2 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using MBL2 antibody.

• 

  Immunohistochemistry of paraffin-embedded mouse stomach using MBL2 antibody.

• 

  Immunohistochemistry of paraffin-embedded human liver injury using MBL2 antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50 - 1:100
• Reactivities: Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human MBL2
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 26 kDa
• Gene Name: mannose binding lectin 2
• Database Link:
  NP_000233
  Entrez Gene 64668 RatEntrez Gene 4153 Human
  UniProt ID P11226
• Background: This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.
• Synonyms: COLEC1; HSMBPC; MBL; MBL2D; MBP; MBP-C; MBP1; MBPD

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Complement and coagulation cascades